S01 → Blue Dot/White Tangerine
From the Microscope to the Telescope
→ Case Studies
Selected Case Studies are available upon request.
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Space Migraines and Headaches
project conducted with the International Centre for Astronautical Development
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Several potential catalysts for migraines and other occasional headaches exist, encompassing nitric oxide, alcohol consumption, hormonal variations, post-stress relaxation, physical activity, exhaustion, abrupt changes in barometric pressure, and acute alterations in sleep or dietary habits. While space travel is not recognised as a trigger of migraines per se, there are anecdotal accounts of severe headaches occurring during space journeys. Typically, these headaches are attributed to the Space Motion Sickness (SMS) syndrome and can disturb the everyday activities of astronauts/cosmonauts, particularly during or after Extravehicular Activities (EVAs). This case study summarises how to prevent and minimise migraines in the space environment.
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Magnetic Resonance Imaging for the Brain in Space
project conducted at King’s College London
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From understanding neuroplasticity to tracking the effects of microgravity and cosmic radiation, this case study proposes a comprehensive review of the use of Magnetic Resonance Imaging (MRI) to explore the structural and functional aspects of the space traveller’s brain and highlight how the space environment can impact cerebrospinal fluid and neural health.
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Vagus Nerve and Vagal Baroreflex Function
project conducted at King’s College London
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The vagus nerve, also known as the tenth cranial nerve or CN X, is the longest cranial nerve in the body and a major component of the parasympathetic nervous system. It plays a crucial role in regulating heart rate, gastrointestinal motility, and respiratory function, among other autonomic functions. One key aspect discussed here is the vagal baroreflex, which is responsible for modulating heart rate and blood pressure in response to changes in blood volume and pressure. In the microgravity environment of space, alterations in fluid distribution and cardiovascular dynamics can challenge the effectiveness of the vagal baroreflex, potentially resulting in orthostatic intolerance and other cardiovascular issues. This case study explores various methodologies employed to assess autonomic nervous system activity in space, including heart rate variability analysis, baroreflex sensitivity measurements, and other physiological monitoring techniques.
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Designing for Humans and their Environments
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From medical devices used in Antarctica to mission control desks in spaceships, people in extreme environments are not ordinary users. In addition to facing technical and environmental challenges, the psychological burden inherent to risk factors such as isolation, confinement and deprivation requires specific design solutions and the growth of new usability habits. “Stress, Fatigue, and Interfaces: Designing for Humans and their Environments” explore the intricate relationship between humans and their environments and how the concepts of functionality and usability provide valuable insights for creating user-friendly and stress-reducing systems that enhance human health and productivity in extreme environments.